The cannabis B2B market is booming – we're talking $102 billion by 2030 with over 20% growth year after year since 2021. Pretty impressive, right? But here's the thing: if you're still managing your cannabis business relationships through a maze of spreadsheets, text messages, and endless email chains, you're missing out on some serious efficiency.
Cannabis B2B platforms have transformed from "nice-to-have" tools to essential systems that connect everyone in the supply chain. They're helping cultivators, processors, distributors, and retailers work together more seamlessly than ever before – especially important in an industry with so many regulatory hoops to jump through.
In this guide, we'll walk you through the top cannabis B2B platforms making waves in 2025. Whether you need to expand your distribution network, make your supply chain run smoother, or connect with new business partners, we've got you covered. By the time you finish reading, you'll know exactly which solutions might work best for your business needs.
Understanding Cannabis B2B: A Quick Overview
Think of cannabis B2B platforms as the digital connectors for our industry. They're bridging all the gaps between businesses in the supply chain and handling the unique headaches we deal with in cannabis—like those ever-changing regulations, inventory tracking, and all the compliance paperwork that makes us want to pull our hair out.
These platforms typically come in a few different flavors:
Cannabis Wholesale platforms are where brands, distributors, and retailers find each other and do business. Instead of the old days of calling or texting dozens of vendors to find products, you can browse, order, and manage all your relationships in one place.
Supply Chain Management Solutions track everything from seed to sale. They help you keep tabs on cannabis inventory, manage transfers between facilities, and stay compliant with those state regulations that seem to change every other week.
Industry Networking Platforms focus more on connections than transactions. They help you meet potential partners, stay on top of what's happening in the industry, and build relationships that can lead to new opportunities.
Why should you care about these cannabis wholesale platforms? The benefits are pretty obvious once you start using them:
- You save so much time it's not even funny. No more spending half your day chasing down products or confirming orders.
- Your network suddenly expands dramatically. You get access to hundreds or thousands of potential business partners across multiple markets.
- Price transparency becomes the norm. You can easily compare what different suppliers are offering to make sure you're getting a fair deal.
- Compliance gets way easier. Most platforms have built-in tools to help you follow state-specific rules and avoid those expensive mistakes.
- You get data you can actually use. You'll see insights into market trends, product performance, and business opportunities you'd probably miss otherwise.
As the cannabis industry grows up, these platforms aren't optional extras anymore—they're must-haves. They're the difference between running your business on professional systems versus the old-school scramble of scattered communications and manual processes. Let's look at some of the best options out there.
Top Cannabis B2B Wholesale Platforms for 2025
Which platforms are actually leading the wholesale cannabis market in 2025? We'll focus especially on the ones changing how we all buy and sell products across the supply chain.
Distru: End-to-End Cannabis ERP Solution
At Distru, we’re more than just another cannabis platform— we’re an all-in-one ERP solution built specifically for the cannabis industry. Our wholesale e-commerce menu can work as a standalone tool or seamlessly integrate with the rest of our platform. That kind of flexibility is a game changer when you're figuring out what your business truly needs.
Distru Commerce
So, what makes our cannabis wholesale menu so powerful? For starters, it’s fully customizable to match your brand. You can highlight your products with detailed descriptions and visuals, and organize everything in a way that fits your unique workflow. Best of all, the menu syncs in real-time with your inventory, so you’ll never have to tell a client, “Actually, we’re out of stock” again.
The mobile-responsive design is another win — your customers can place orders from anywhere. Whether they're working late at home, on the dispensary floor, or out visiting clients, they can pull up your menu and place an order on the spot. More flexibility = more orders and fewer missed opportunities.
Plenty of cannabis businesses use Distru alongside other B2B tools because our platform integrates smoothly across your entire tech stack. That means no more duplicate data entry, no more mismatched records — just clean, connected operations that let you focus on growth.
Other Cannabis Wholesale Marketplaces
While Distru offers this comprehensive approach, there are other players in the cannabis B2B space worth knowing about. LeafLink has built up a pretty massive marketplace where retailers can discover products, place orders from different brands, and manage vendor relationships all in one spot. They've got a huge footprint across most legal states and process billions in orders annually.
Apex Trading takes a different approach by combining specialized wholesale tools with their technology platform. They're not just connecting buyers and sellers digitally - they're providing a complete business management solution for cannabis brands and cultivators across multiple states. This model helps brands streamline their sales processes while retailers benefit from an organized procurement experience.
LeafLink
If you've been in cannabis for more than five minutes, you've probably heard of LeafLink. They've built themselves into one of the largest cannabis B2B platforms out there - we're talking over 2,500 brands and 7,500 retailers on their marketplace. They were processing something like $5 billion in annual orders across pretty much every legal market in the US. As a retailer, you can log in and instantly access thousands of brands, compare products, and place orders from multiple vendors in a single cart. For brands and distributors, it's a massive channel to showcase your products and reach retailers you might never connect with otherwise.
LeafLink goes beyond just basic ordering with a pretty robust suite of features. Their CRM tools help you keep track of all your customer relationships, while their reporting gives you insights into sales trends, popular products, and customer behavior. They've also developed some financing and payment solutions, which is a big deal in an industry where traditional banking is still such a headache. Their market insights reports leverage data from thousands of transactions, giving you visibility you just couldn't get elsewhere when you're trying to figure out what products to stock or develop next.
Distru ERP is integrated with LeafLink, allowing for seamless data flow between your inventory management system and the marketplace.
Apex Trading
Apex Trading takes a comprehensive approach to cannabis B2B - they're combining wholesale marketplace functionality with robust business management tools. Instead of just connecting buyers and sellers digitally, they've built a platform that helps cannabis brands manage their entire wholesale operation. If you're a brand or cultivator, Apex Trading lets you showcase products, manage inventory across multiple facilities, process orders, and handle logistics all from one platform. For retailers, the benefit is a streamlined procurement process with access to product details, COAs, and simplified ordering from multiple vendors. Apex is integrated with Distru ERP, providing a connected ecosystem that streamlines operations between your marketplace activities and back-office inventory management.
Cannabis Supply Chain Platforms
Let’s discuss the supply chain - it's not the most interesting topic, but in cannabis, it can absolutely make or break your business. When you're dealing with a plant that's tracked from seed to sale and regulated at every step, having the right tools isn't a luxury - it's survival.
Distru: Powering the Cannabis Supply Chain with Advanced Technology
Distru really shines when it comes to managing the cannabis supply chain. Think about all the headaches you face - knowing what inventory you have where, transferring products between facilities, keeping up with compliance paperwork - Distru tackles all of these day-to-day challenges.
Whether you're a cultivator, processor, distributor, vertically integrated operator, microbusiness, or MSO, Distru gives you the visibility and control you need to scale. Real-time inventory tracking across locations? Done. Product transfers with automated compliance docs? Easy. Need your COAs or batch data? Already attached.
Distru connects with the tools you already use—like Metrc, BioTrack, and QuickBooks—and integrates with leading retail POS systems like Dutchie, Treez, and Blaze. That means no more double data entry, fewer errors, and faster workflows from seed to sale.
From Back-End Ops to Wholesale Sales
Distru doesn’t stop at operations. With Distru Commerce, our latest launch, you get a wholesale menu designed to boost sales across your supply chain. Showcase your live inventory, take orders, and collaborate with buyers—right inside Distru. It’s like having a wholesale rep on autopilot.
Stay Compliant. Stay Synced. Stay Selling.
Distru helps you stay ahead of compliance by syncing with state traceability systems and surfacing insights before they become problems. Track slow-moving SKUs, identify bottlenecks, and make smart moves backed by data.
But the real magic? Everyone’s on the same page. Your team, your partners, your buyers—Distru keeps them connected in one system built for cannabis, by cannabis professionals.
Cannabis Business Software Solutions
Beyond the cool factor of working with cannabis, there's the daily reality of managing operations, staying compliant, and making smart decisions based on actual data. Here's how Distru is changing the game.
Distru: All-in-One Cannabis Business Management Software
Cannabis business owners often build their tech stack one solution at a time. But what if you could get everything you need in one place? Imagine a one-stop software shop that covers inventory tracking, compliance, order management, and more. That’s exactly what we built Distru to be — a complete, all-in-one platform for cannabis operators.
All-in-One Operations, Built for Cannabis
Our Order Management system streamlines your entire sales workflow — from the first customer inquiry to the moment the product is out the door. Meanwhile, our Inventory Control gives you real-time visibility across every location, so you’re never caught selling out-of-stock products or sitting on forgotten excess inventory.
Our B2B e-Commerce Menu acts as the gateway to it all — giving your buyers a branded, user-friendly experience while keeping your data in sync with the rest of your operations.
Cannabis Compliance, Without the Headaches
Let’s face it — compliance in the cannabis world is a beast. That’s why we handle it for you. Distru automatically generates the compliance documentation you need, tracks inventory according to state-specific regulations, manages testing data, and even handles complex tax rules unique to the cannabis industry.
Our platform connects to state track-and-trace systems (like Metrc or BioTrack), accounting tools, POS systems, and more — all through our robust API. That means less manual work, fewer errors, and a smoother flow of data across your entire business.
Trusted by Operators Like You
Operators who switch to Distru consistently report the same wins: less paperwork, fewer order mistakes, stronger compliance, and better decision-making driven by real-time data — not gut instinct. Whether you're just getting started or scaling across states, our platform grows with you.
While many cannabis software tools only solve one problem, Distru is built to handle everything. You won’t have to cobble together disconnected systems that don’t speak the same language. With Distru, you get one seamless solution from seed to sale.
Easy Onboarding, Ongoing Support
Getting started with Distru is easier than you think. Our team walks you through implementation, and the platform is intuitive enough for your entire team — even the non-techy folks. As cannabis regulations evolve (because they always do), we stay ahead with regular updates so you’re always in compliance.
Growing with the Right Partners
At the core of every great cannabis business is the right network of partners. While Distru gives you the tools to stay competitive, success also depends on who you work with. We’ll help you stay connected and supported as you grow — because in this industry, collaboration is everything.
Choosing the Right Cannabis B2B Platform for Your Business
B2B platforms aren't just nice-to-have toys anymore - they're essential tools for any cannabis business that wants to grow and thrive. When you're shopping around, think about what specific challenges you're trying to solve, where you operate (and plan to expand), what features you absolutely need, how well the platform will play with your existing systems, and whether it has compliance tools designed for your specific state's regulations. Distru consistently stands out by offering comprehensive solutions that cover everything from wholesale to supply chain management to business operations. What's particularly valuable is how Distru can both solve your immediate pressing issues and grow with your business over time, making it a true partner in your success rather than just another vendor charging you a monthly fee.
